期刊
NATURAL PRODUCT RESEARCH
卷 32, 期 9, 页码 997-1003出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2017.1375916
关键词
Xanthoceras sorbifolia Bunge; 16-deoxybarringtogenol C; carbohydrate chain; cytotoxicity
The Xanthoceras sorbifolia Bunge husks were known for their abundant triterpenoids resource, which contributed to many bioactivities, such as antitumor, antiinflammatory and neuroprotection. The present study has led to the purification of a new triterpenoid saponin, 21-O-acetyl-xanthohuskiside A (1), together with six known barrigenol derivatives (2-7), whose structures were authenticated on the basis of NMR, HR-MS, IR spectrum and acid hydrolysis experiment. Compound 7 showed more noteworthy cytotoxicity towards three human tumour cell lines (HCT-116, HepG-2 and U87-MG) than other compounds. [GRAPHICS] .
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