4.4 Article

Isotryptophan from Antarctic Bacillus amyloliquefaciens Pc3: purification, identification, characterization, and antifungal activity

期刊

NATURAL PRODUCT RESEARCH
卷 31, 期 18, 页码 2153-2157

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2016.1274896

关键词

Isotryptophan; antifungal activity; Antarctic; plant-pathogenic fungi; Bacillus amyloliquefaciens

资金

  1. National Key Basic Research Program of China ('973'-Program) [2015CB755903]
  2. Scientific Research Project of the Marine Public Welfare Industry of China [201205020]
  3. Natural Science Foundation of China [41306166]
  4. Natural Science Foundation of Fujian Province, China [2016J05079]

向作者/读者索取更多资源

Strain Pc3 was isolated from Antarctic seawater and identified as Bacillus amyloliquefaciens. A compound with antifungal activity was purified from the fermentation supernatant of B. amyloliquefaciens Pc3. Its structure was determined to be (S)-2-amino-3-(1H-indol-2-yl) propanoic acid, named as isotryptophan, based on detailed analysis of its nuclear magnetic resonance (NMR) and high-resolution electrospray ionisation mass spectrometry (HR-ESI-MS). Isotryptophan exhibited good thermal stability and antifungal activity against several plant-pathogenic fungi with low minimum inhibitory concentrations. Therefore, the characterisation of isotryptophan from the Antarctic B. amyloliquefaciens Pc3 will facilitate its potential application in the control of plant-pathogenic fungal infection. [GRAPHICS] .

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