期刊
NANO TODAY
卷 12, 期 -, 页码 10-13出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.nantod.2016.06.007
关键词
3Rs; Alternative approaches; Nanotoxicology; Nanosafety; Regulatory testing
Due to the plethora of nanomaterials being manufactured, it is crucial that their effects on human health are understood. It is not feasible to assess the safety of all nanomaterials using animal-based toxicity tests. There are also scientific, business, legislative and ethical drivers to reconsider the use of such toxicity tests. Utilising non-traditional methods has the potential to improve the human relevance of nanosafety assessment, reduce the numbers of animals that are used, and shift the paradigm to a '21st century' approach that exploits recent scientific and technological advances. This article considers how application of the 3Rs principles can be used as a framework to support and guide this paradigm shift in the short, medium and long-term. Bringing the community together to facilitate the transition is necessary to ensure that tangible impacts are made on the efficiency and robustness of the nanosafety assessment process. (C) 2016 The Authors. Published by Elsevier Ltd.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据