期刊
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
卷 772, 期 -, 页码 3-12出版社
ELSEVIER
DOI: 10.1016/j.mrrev.2016.07.002
关键词
Human papillomavirus; Cervical cancer; Oncogene; Tumor suppressor; Epithelial differentiation; Vaccine
资金
- PHS grant [R01 CA066980]
- [F31 CA180516]
Human papillomaviruses are small DNA viruses with a tropism for squamous epithelia. A unique aspect of human papillomavirus molecular biology involves dependence on the differentiation status of the host epithelial cell to complete the viral lifecycle. A small group of these viruses are the etiologic agents of several types of human cancers, including oral and anogenital tract carcinomas. This review focuses on the basic molecular biology of human papillomaviruses. (C) 2016 Elsevier B.V. All rights reserved.
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