期刊
MUSCLE & NERVE
卷 57, 期 2, 页码 255-259出版社
WILEY
DOI: 10.1002/mus.25724
关键词
Charcot-Marie-Tooth disease; foot deformities; foot surgery; orthopedic complications; pes cavus; survey
资金
- National Institutes of Neurological Diseases and Stroke and Office of Rare Diseases [U54NS065712]
- Medical Research Council [G0601943]
- National Institute for Health Research University College London Hospitals Biomedical Research Centre
- NCATS
- NINDS
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [U54NS065712] Funding Source: NIH RePORTER
- National Institute for Health Research [CAT CL09-21] Funding Source: researchfish
- MRC [G0601943] Funding Source: UKRI
Introduction: Foot deformities are frequent complications in Charcot-Marie-Tooth disease (CMT) patients, often requiring orthopedic surgery. However, there are no prospective, randomized studies on surgical management, and there is variation in the approaches among centers both within and between countries. Methods: In this study we assessed the frequency of foot deformities and surgery among patients recruited into the Inherited Neuropathies Consortium (INC). We also designed a survey addressed to orthopedic surgeons at INC centers to determine whether surgical approaches to orthopedic complications in CMT are variable. Results: Foot deformities were reported in 71% of CMT patients; 30% of the patients had surgery. Survey questions were answered by 16 surgeons working in different specialized centers. Most of the respondents were foot and ankle surgeons. There was marked variation in surgical management. Discussion: Our findings confirm that the approaches to orthopedic management of CMT are varied. We identify areas that require further research.
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