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Alopecias in lupus erythematosus

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LUPUS SCIENCE & MEDICINE
卷 5, 期 1, 页码 -

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BMJ PUBLISHING GROUP
DOI: 10.1136/lupus-2018-000291

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  1. US Department of Veterans Affairs (Veterans Health Administration)
  2. US Department of Veterans Affairs (Office of Research and Development)
  3. US Department of Veterans Affairs (Biomedical Laboratory Research and Development)
  4. NIH [RO1AR071653]

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Several patterns of hair loss can occur in lupus erythematosus (LE). Alopecias which show histological characteristics of LE are LE-specific, and include discoid LE (DLE), diffuse or patchy hair loss in acute LE, subacute cutaneous LE, and rarely tumid LE. Lupus hair in SLE is a poorly characterised entity and may be a form of telogen effluvium. Alopecia areata can coexist with LE and may mimic DLE. Non-lupus alopecias such as telogen effluvium and anagen effluvium have a myriad of causes which include disease flares, drugs and stress in the setting of LE. The latest validated Systemic Lupus International Collaborating Clinics classification criteria for SLE includes non-scarring alopecia as a criterion; therefore, recognising the aetiology of hair loss in the setting of LE is crucial in classifying a patient to have systemic disease.

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