期刊
MOLECULES
卷 22, 期 10, 页码 -出版社
MDPI
DOI: 10.3390/molecules22101743
关键词
antimicrobial; chronic infection; diabetes; peptides; ulcers; wound-healing; skin and soft tissue infections (SSTI)
资金
- Fundacao para a Ciencia e Tecnologia (FCT, Portugal) [UID/QUI/50006/2013, PD/BD/135073/2017]
- Comissao de Coordenacao e Desenvolvimento Regional do Norte (CCDR-N)/NORTE/Portugal through project DESignBIOtechHealth [Norte-01-0145-FEDER-000024]
- Fundação para a Ciência e a Tecnologia [PD/BD/135073/2017] Funding Source: FCT
As the incidence of diabetes continues to increase in the western world, the prevalence of chronic wounds related to this condition continues to be a major focus of wound care research. Additionally, over 50% of chronic wounds exhibit signs and symptoms that are consistent with localized bacterial biofilms underlying severe infections that contribute to tissue destruction, delayed wound-healing and other serious complications. Most current biomedical approaches for advanced wound care aim at providing antimicrobial protection to the open wound together with a matrix scaffold (often collagen-based) to boost reestablishment of the skin tissue. Therefore, the present review is focused on the efforts that have been made over the past years to find peptides possessing wound-healing properties, towards the development of new and effective wound care treatments for diabetic foot ulcers and other skin and soft tissue infections.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据