相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential
Yangbo Feng et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
DL0805-2,a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes
Tian-yi Yuan et al.
ACTA PHARMACOLOGICA SINICA (2016)
Amino acid derived quinazolines as Rock/PKA inhibitors
Sarwat Chowdhury et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Cardiovascular effects of a novel selective Rho kinase inhibitor, 2-(1H-indazole-5-yl)amino-4-methoxy-6-piperazino triazine (DW1865)
Kwang-Seok Oh et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Synthesis and Biological Evaluation of Urea Derivatives as Highly Potent and Selective Rho Kinase Inhibitors
Yan Yin et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
The Vasorelaxant Mechanisms of a Rho Kinase Inhibitor DL0805 in Rat Thoracic Aorta
Lili Gong et al.
MOLECULES (2012)
Efficient synthesis of [11C]H-1152, a PET probe specific for Rho-kinases, highly potential targets in diagnostic medicine and drug development
Masaaki Suzuki et al.
TETRAHEDRON (2012)
Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors
Xingang Fang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I)
Sarwat Chowdhury et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Rho kinase and hypertension
Angela Wirth
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
The development of benzimidazoles as selective rho kinase inhibitors
E. Hampton Sessions et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
2,3-Diaminopyrazines as rho kinase inhibitors
Alan J. Henderson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: Part 3, aryl substituted pyrrolidines
Todd Bosanac et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Biochemical, Cellular, and Anti-Inflammatory Properties of a Potent, Selective, Orally Bioavailable Benzamide Inhibitor of Rho Kinase Activity
Lakshman E. Rajagopalan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors
Yan Yin et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers
Hidenobu Tanihara et al.
ARCHIVES OF OPHTHALMOLOGY (2008)
Benzimidazole- and benzoxazole-based inhibitors of Rho kinase
E. Hampton Sessions et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Chroman-3-amides as potent Rho kinase inhibitors
Yen Ting Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension
M. Oka et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Synthesis of potential Rho-kinase inhibitors based on the chemistry of an original heterocycle:: 4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one
Marie-Anne Letellier et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2008)
Targeting cerebrovascular Rho-kinase in stroke
Hwa Kyoung Shin et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2008)
Potent, Selective and Orally Bioavailable Dihydropyrimidine Inhibitors of Rho Kinase (ROCK1) as Potential Therapeutic Agents for Cardiovascular Diseases
Clark A. Sehon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Structure-activity relationships, and drug metabolism and pharmacokinetic properties for indazole piperazine and indazole piperidine inhibitors of ROCK-II
Yangbo Feng et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Design and synthesis of rho kinase inhibitors (III)
Masayuki Iwakubo et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors
Krista B. Goodman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Design and synthesis of Rho kinase inhibitors (II)
Masayuki Iwakubo et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
The Rho kinase inhibitor fasudil inhibits tumor progression in human and rat tumor models
Han Ying et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Design and synthesis of Rho kinase inhibitors (I)
A Takami et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Rocks: Multifunctional kinases in cell behaviour
K Riento et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants
AV Somlyo et al.
FASEB JOURNAL (2003)
Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase
M Waki et al.
CURRENT EYE RESEARCH (2001)
Y-27632 potentiates relaxant effects of β2-adrenoceptor agonists in bovine tracheal smooth muscle
T Nakahara et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
分享论文
