4.7 Article

A single-step multi-level supramolecular system for cancer sonotheranostics

期刊

NANOSCALE HORIZONS
卷 4, 期 1, 页码 190-195

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8nh00276b

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资金

  1. National Key Research and Development Program of China [2017YFA0205201, 2018YFA0107301]
  2. National Natural Science Foundation of China [81422023, 81371596, U1705281, U1505221]
  3. Fundamental Research Funds for the Central Universities [20720160065, 20720150141]
  4. Program for New Century Excellent Talents in University, China [NCET-13-0502]

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A multi-level supramolecular system produced by single-step Fe3+-mediated ionic crosslinking self-assembly can overcome the critical issues of current sonodynamic therapy (SDT) and address the need to monitor therapeutic effects in vivo with a non-invasive approach. This rational design of organic sonosensitizer-based formulation shows great potential for clinical SDT against deep-seated cancer.

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