4.6 Review

Therapeutic potential of autophagy-enhancing agents in Parkinson's disease

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Mammalian Autophagy: How Does It Work?

Carla F. Bento et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)

Review Cell Biology

Recent insights into the function of autophagy in cancer

Ravi Amaravadi et al.

GENES & DEVELOPMENT (2016)

Article Biochemistry & Molecular Biology

Mitophagy and the therapeutic clearance of damaged mitochondria for neuroprotection

Daniel A. East et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2016)

Review Biochemistry & Molecular Biology

Molecular changes in the postmortem parkinsonian brain

Damien Toulorge et al.

JOURNAL OF NEUROCHEMISTRY (2016)

Review Biochemistry & Molecular Biology

Parkinson's disease: acid-glucocerebrosidase activity and alpha-synuclein clearance

Judith Blanz et al.

JOURNAL OF NEUROCHEMISTRY (2016)

Review Clinical Neurology

Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies

Maria Xilouri et al.

MOVEMENT DISORDERS (2016)

Review Cell Biology

Mechanistic insights into selective autophagy pathways: lessons from yeast

Jean-Claude Farre et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

Brian J. DeBosch et al.

SCIENCE SIGNALING (2016)

Review Cell Biology

Ubiquitin-Dependent And Independent Signals In Selective Autophagy

Aliaksandr Khaminets et al.

TRENDS IN CELL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis

Brian J. DeBosch et al.

SCIENCE SIGNALING (2016)

Article Biochemistry & Molecular Biology

Trehalose intake induces chaperone molecules along with autophagy in a mouse model of Lewy body disease

Kunikazu Tanji et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Neurosciences

Glucocerebrosidase and Parkinson disease: Recent advances

Anthony H. V. Schapira

MOLECULAR AND CELLULAR NEUROSCIENCE (2015)

Article Neurosciences

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

Emily M. Rocha et al.

NEUROBIOLOGY OF DISEASE (2015)

Article Clinical Neurology

The contribution of Niemann-Pick SMPD1 mutations to Parkinson disease in Ashkenazi Jews

E. Dagan et al.

PARKINSONISM & RELATED DISORDERS (2015)

Article Multidisciplinary Sciences

Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein

Kiri Kilpatrick et al.

PLOS ONE (2015)

Review Neurosciences

Autophagic activity in neuronal cell death

Robert W. Button et al.

NEUROSCIENCE BULLETIN (2015)

Review Neurosciences

Potential application of lithium in Parkinson's and other neurodegenerative diseases

Carol A. Lazzara et al.

FRONTIERS IN NEUROSCIENCE (2015)

Review Biochemistry & Molecular Biology

Autosis and autophagic cell death: the dark side of autophagy

Y. Liu et al.

CELL DEATH AND DIFFERENTIATION (2015)

Article Biochemistry & Molecular Biology

(Poly)phenols protect from α-synuclein toxicity by reducing oxidative stress and promoting autophagy

Diana Macedo et al.

HUMAN MOLECULAR GENETICS (2015)

Article Genetics & Heredity

Significant Study of Population Stratification, Sensitivity Analysis and Trim and Fill Analyses on GBA Mutation and Parkinson's Disease

Jie Liu et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2014)

Article Biochemistry & Molecular Biology

Effect of resveratrol on mitochondrial function: Implications in parkin-associated familiar Parkinson's disease

Anna Ferretta et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)

Review Clinical Neurology

Glucocerebrosidase is shaking up the synucleinopathies

Marina Siebert et al.

Article Cell Biology

Spermidine protects against α-synuclein neurotoxicity

Sabrina Buettner et al.

CELL CYCLE (2014)

Article Biochemistry & Molecular Biology

PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy

Daniel A. East et al.

CHEMISTRY & BIOLOGY (2014)

Review Pharmacology & Pharmacy

Lithium: A review of pharmacology, clinical uses, and toxicity

Ramadhan Oruch et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2014)

Article Biochemistry & Molecular Biology

Resveratrol Partially Prevents Rotenone-Induced Neurotoxicity in Dopaminergic SH-SY5Y Cells through Induction of Heme Oxygenase-1 Dependent Autophagy

Tsu-Kung Lin et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Biochemistry & Molecular Biology

2-Hydroxypropyl-β-cyclodextrin Promotes Transcription Factor EB- mediated Activation of Autophagy

Wensi Song et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Clinical Neurology

Cerebrospinal Fluid Lysosomal Enzymes and Alpha-Synuclein in Parkinson's Disease

Lucilla Parnetti et al.

MOVEMENT DISORDERS (2014)

Article Neurosciences

The protective role of AMP-activated protein kinase in alpha-synuclein neurotoxicity in vitro

Marija Dulovic et al.

NEUROBIOLOGY OF DISEASE (2014)

Article Clinical Neurology

A GCase Chaperone Improves Motor Function in a Mouse Model of Synucleinopathy

Franziska Richter et al.

NEUROTHERAPEUTICS (2014)

Article Multidisciplinary Sciences

LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance

Michelle Rothaug et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Cell Biology

Macrophage Models of Gaucher Disease for Evaluating Disease Pathogenesis and Candidate Drugs

Elma Aflaki et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Article Multidisciplinary Sciences

Glucocerebrosidase depletion enhances cell-to-cell transmission of α-synuclein

Eun-Jin Bae et al.

NATURE COMMUNICATIONS (2014)

Article Clinical Neurology

Therapeutic Prospects for Parkinson Disease

C. Warren Olanow et al.

ANNALS OF NEUROLOGY (2013)

Article Clinical Neurology

The chaperone activity and toxicity of ambroxol on Gaucher cells and normal mice

Zhuo Luan et al.

BRAIN & DEVELOPMENT (2013)

Article Biochemistry & Molecular Biology

Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy

Selcuk A. Tanik et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Neurosciences

Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship

Maria Xilouri et al.

MOLECULAR NEUROBIOLOGY (2013)

Article Biochemistry & Molecular Biology

Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain

J. W. Steele et al.

MOLECULAR PSYCHIATRY (2013)

Article Biochemistry & Molecular Biology

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Jaime Anguiano et al.

NATURE CHEMICAL BIOLOGY (2013)

Review Biochemistry & Molecular Biology

The role of autophagy in neurodegenerative disease

Ralph A. Nixon

NATURE MEDICINE (2013)

Article Neurosciences

Interplay of LRRK2 with chaperone-mediated autophagy

Samantha J. Orenstein et al.

NATURE NEUROSCIENCE (2013)

Article Neurosciences

The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy

Victoria S. Burchell et al.

NATURE NEUROSCIENCE (2013)

Review Clinical Neurology

Advances in the genetics of Parkinson disease

Joanne Trinh et al.

NATURE REVIEWS NEUROLOGY (2013)

Article Geriatrics & Gerontology

A rare lysosomal enzyme gene SMPD1 variant (p.R591C) associates with Parkinson's disease

Jia-Nee Foo et al.

NEUROBIOLOGY OF AGING (2013)

Letter Medicine, General & Internal

Autophagy in Human Health and Disease REPLY

Augustine M. K. Choi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Editorial Material Multidisciplinary Sciences

Glucocerebrosidase in the pathogenesis and treatment of Parkinson disease

Anthony H. V. Schapira et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies

S. Pablo Sardi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

Abid Oueslati et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

Mickael Decressac et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Biochemistry & Molecular Biology

mTOR: on target for novel therapeutic strategies in the nervous system

Kenneth Maiese et al.

TRENDS IN MOLECULAR MEDICINE (2013)

Article Neurosciences

ATP13A2 (PARK9) protein levels are reduced in brain tissue of cases with Lewy bodies

Karen E. Murphy et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2013)

Review Medicine, General & Internal

MECHANISMS OF DISEASE Autophagy in Human Health and Disease

Augustine M. K. Choi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Neurosciences

mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats

Mickael Decressac et al.

JOURNAL OF PARKINSONS DISEASE (2013)

Review Clinical Neurology

Protein degradation pathways in Parkinson's disease: curse or blessing

Darius Ebrahimi-Fakhari et al.

ACTA NEUROPATHOLOGICA (2012)

Article Clinical Neurology

Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains

Matthew E. Gegg et al.

ANNALS OF NEUROLOGY (2012)

Review Biochemistry & Molecular Biology

mTOR Signaling in Growth Control and Disease

Mathieu Laplante et al.

Review Biochemistry & Molecular Biology

Microautophagy: lesser-known self-eating

Wen-wen Li et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2012)

Article Biochemistry & Molecular Biology

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

Carmine Settembre et al.

EMBO JOURNAL (2012)

Article Neurosciences

Latrepirdine (Dimebon™) Enhances Autophagy and Reduces Intracellular GFP-Aβ42 Levels in Yeast

Prashant R. Bharadwaj et al.

JOURNAL OF ALZHEIMERS DISEASE (2012)

Article Biochemistry & Molecular Biology

Ex Vivo and in Vivo Effects of Isofagomine on Acid β-Glucosidase Variants and Substrate Levels in Gaucher Disease

Ying Sun et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Cell Biology

Life in the balance - a mechanistic view of the crosstalk between autophagy and apoptosis

Assaf D. Rubinstein et al.

JOURNAL OF CELL SCIENCE (2012)

Review Biochemistry & Molecular Biology

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

Sebastian Alers et al.

MOLECULAR AND CELLULAR BIOLOGY (2012)

Review Biotechnology & Applied Microbiology

Autophagy modulation as a potential therapeutic target for diverse diseases

David C. Rubinsztein et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Article Biochemistry & Molecular Biology

Effect of Trehalose on PC12 Cells Overexpressing Wild-Type or A53T Mutant α-synuclein

Dan-Mei Lan et al.

NEUROCHEMICAL RESEARCH (2012)

Article Medicine, Research & Experimental

The Role of Autophagy in Parkinson's Disease

Melinda A. Lynch-Day et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Review Oncology

Deconvoluting the context-dependent role for autophagy in cancer

Eileen White

NATURE REVIEWS CANCER (2012)

Article Cell Biology

Systems biology of the autophagy-lysosomal pathway

Anil G. Jegga et al.

AUTOPHAGY (2011)

Article Biochemistry & Molecular Biology

Mutant A53T α-Synuclein Induces Neuronal Death by Increasing Mitochondrial Autophagy

Vinay Choubey et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Neurosciences

Akt Suppresses Retrograde Degeneration of Dopaminergic Axons by Inhibition of Macroautophagy

Hsiao-Chun Cheng et al.

JOURNAL OF NEUROSCIENCE (2011)

Article Cell Biology

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim et al.

NATURE CELL BIOLOGY (2011)

Review Neurosciences

Fighting neurodegeneration with rapamycin: mechanistic insights

Jordi Bove et al.

NATURE REVIEWS NEUROSCIENCE (2011)

Article Neurosciences

Alteration of autophagosomal proteins (LC3, GABARAP and GATE-16) in Lewy body disease

Kunikazu Tanji et al.

NEUROBIOLOGY OF DISEASE (2011)

Article Biochemistry & Molecular Biology

Resveratrol-Activated AMPK/SIRT1/Autophagy in Cellular Models of Parkinson's Disease

Yuncheng Wu et al.

NEUROSIGNALS (2011)

Article Multidisciplinary Sciences

CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

S. Pablo Sardi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre et al.

SCIENCE (2011)

Article Clinical Neurology

Chaperone-Mediated Autophagy Markers in Parkinson Disease Brains

Lydia Alvarez-Erviti et al.

ARCHIVES OF NEUROLOGY (2010)

Article Neurosciences

Rapamycin Protects against Neuron Death in In Vitro and In Vivo Models of Parkinson's Disease

Cristina Malagelada et al.

JOURNAL OF NEUROSCIENCE (2010)

Article Neurosciences

Pathogenic Lysosomal Depletion in Parkinson's Disease

Benjamin Dehay et al.

JOURNAL OF NEUROSCIENCE (2010)

Review Physiology

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

Brinda Ravikumar et al.

PHYSIOLOGICAL REVIEWS (2010)

Article Neurosciences

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss

Luke S. Tain et al.

NATURE NEUROSCIENCE (2009)

Article Medicine, General & Internal

Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

E. Sidransky et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Multidisciplinary Sciences

A Gene Network Regulating Lysosomal Biogenesis and Function

Marco Sardiello et al.

SCIENCE (2009)

Article Biochemistry & Molecular Biology

Inhibition of mTOR Signaling in Parkinson's Disease Prevents L-DOPA-Induced Dyskinesia

Emanuela Santini et al.

SCIENCE SIGNALING (2009)

Article Biochemistry & Molecular Biology

Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells

Tereza Vogiatzi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Cell Biology

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

Eisuke Itakura et al.

MOLECULAR BIOLOGY OF THE CELL (2008)

News Item Biochemistry & Molecular Biology

Small molecule enhancers of autophagy for neurodegenerative diseases

Sovan Sarkar et al.

MOLECULAR BIOSYSTEMS (2008)

Article Biochemistry & Molecular Biology

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

Andrea Williams et al.

NATURE CHEMICAL BIOLOGY (2008)

Review Neurosciences

Ambroxol: A CNS drug?

Thomas Weiser

CNS NEUROSCIENCE & THERAPEUTICS (2008)

Article Neurosciences

Induction of autophagy in neurite degeneration of mouse superior cervical ganglion neurons

Yi Yang et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2007)

Article Clinical Neurology

Lysosomal hydrolases in cerebrospinal fluid from subjects with Parkinson's disease

Chiara Balducci et al.

MOVEMENT DISORDERS (2007)

Article Biochemistry & Molecular Biology

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

Sovan Sarkar et al.

NATURE CHEMICAL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein

Sovan Sarkar et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Multidisciplinary Sciences

The iminosugar isofagomine increases the activity of N370S mutant acid β-glucosidase in Gaucher fibroblasts by several mechanisms

Richard A. Steet et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Loss of autophagy in the central nervous system causes neurodegeneration in mice

Masaaki Komatsu et al.

NATURE (2006)

Article Cell Biology

Lithium induces autophagy by inhibiting inositol monophosphatase

S Sarkar et al.

JOURNAL OF CELL BIOLOGY (2005)

Review Cell Biology

Autophagy: in sickness and in health

AM Cuervo

TRENDS IN CELL BIOLOGY (2004)

Article Multidisciplinary Sciences

Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy

AM Cuervo et al.

SCIENCE (2004)

Article Neurosciences

Dopamine induces autophagic cell death and α-synuclein increase in human neuroblastoma SH-SY5Y cells

C Gómez-Santos et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2003)

Article Biochemistry & Molecular Biology

α-synuclein is degraded by both autophagy and the proteasome

JL Webb et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Cell Biology

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

XS Gao et al.

NATURE CELL BIOLOGY (2002)