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Eliza Barnwell et al.
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Pauline T. Velasco et al.
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Markus P. Kummer et al.
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Johannes vom Berg et al.
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Lennart Mucke et al.
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Dick Terwel et al.
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Markus P. Kummer et al.
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Walter Swardfager et al.
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Neuroinflammatory processes in Alzheimer's disease
Michael T. Heneka et al.
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Hui Ye et al.
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Synaptic degeneration in Alzheimer's disease
Thomas Arendt
ACTA NEUROPATHOLOGICA (2009)
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Ganesh M. Shankar et al.
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Annett Halle et al.
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Transplanted Astrocytes internalize deposited β-amyloid peptides in a transgenic mouse model of Alzheimer's disease
Rea Pihlaja et al.
GLIA (2008)
Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ
M Sastre et al.
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Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice
Michelle C. Janelsins et al.
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S Dudal et al.
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Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein
A Bellucci et al.
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Adult mouse astrocytes degrade amyloid-β in vitro and in situ
T Wyss-Coray et al.
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A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
S Weggen et al.
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Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
MA Chishti et al.
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Alzheimer's disease: Genes, proteins, and therapy
DJ Selkoe
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TE Strandberg et al.
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