期刊
MOLECULAR MICROBIOLOGY
卷 107, 期 1, 页码 24-33出版社
WILEY
DOI: 10.1111/mmi.13869
关键词
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资金
- American Heart Association [15SDG23280044]
- National Institute of Allergy and Infectious Diseases [AI117648]
- Virginia-Maryland College of Veterinary Medicine
- Fralin Life Sciences Institute at Virginia Tech
The AbcR small RNAs (sRNAs) are a fascinating example of two highly conserved sRNAs that differ tremendously at the functional level among organisms. From their transcriptional activation to their regulatory capabilities, the AbcR sRNAs exhibit varying characteristics in three well-studied bacteria belonging to the Rhizobiales order: the plant symbiont Sinorhizobium meliloti, the plant pathogen Agrobacterium tumefaciens, and the animal pathogen Brucella abortus. This review outlines the similarities and differences of the AbcR sRNAs between each of these organisms, and discusses reasons as to why this group of sRNAs has diverged in their genetic organization and regulatory functions across species. In the end, this review will shed light on how regulatory systems, although seemingly conserved among bacteria, can vary based on the environmental niche and lifestyle of an organism.
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