期刊
MOLECULAR MEDICINE REPORTS
卷 15, 期 5, 页码 3366-3371出版社
SPANDIDOS PUBL LTD
DOI: 10.3892/mmr.2017.6383
关键词
benzene; fibers; heavy metals; occupational exposure; epigenetics; cancer
资金
- Lega Italiana per la Lotta contro i Tumori (LILT)
The chronic occupational exposure to contaminants and carcinogens leads to the development of cancer. Over the past decades, many carcinogens have been found in the occupational environment and their presence is often associated with an increased incidence of cancer. According to the International Agency for Research on Cancer (IARC), the majority of carcinogens are classified as 'probable' and 'possible' human carcinogens, while, direct evidence of carcinogenicity is provided in epidemiological and experimental studies. Additionally, accumulating evidence suggests that epigenetic alterations may be early indicators of genotoxic and non-genotoxic carcinogen exposure. In the present review, the relationship between exposures to benzene, mineral fibers, metals and epigenetic alterations are discussed as the most important cancer risk factors during work activities.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据