期刊
MOLECULAR DIAGNOSIS & THERAPY
卷 21, 期 3, 页码 285-294出版社
ADIS INT LTD
DOI: 10.1007/s40291-016-0253-9
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资金
- National Natural Science Foundation of China (NSFC) [81560502]
- National Natural Science Foundation of Yunnan Province [2013FB044, 2014FB008]
- Education Department Fund of Yunnan Province [2014Y165, 2015Z082]
- Doctoral Graduate Academic Newcomer Award of Yunnan Province
Fibrosis is a common pathological state characterized by the excessive accumulation of extracellular matrix components, but the pathogenesis of the disease is still not clear. Previous studies have shown that microRNA-29 (miR-29) can play pivotal roles in the regulation of a variety of organ fibrosis, including cardiac fibrosis, hepatic fibrosis, lung fibrosis, systemic sclerosis, and keloid. In this review, we outline the structure, expression, and regulation of miR-29 as well as its role in fibrotic diseases.
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