期刊
MOLECULAR BIOSYSTEMS
卷 13, 期 12, 页码 2498-2508出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7mb00502d
关键词
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资金
- Singapore A*Star-UK MRC joint Grant (A*Star) [10/1/22/24/630]
- Singapore Ministry of Education Academic Research Fund Tier 1 grant [RG 20/12]
Host immune evasion is a key strategy for the continual survival of many microbial pathogens including Apicomplexan protozoan: Plasmodium spp., the causative agent of Malaria. The malaria parasite has evolved a variety of mechanisms to evade the host immune responses within its two hosts: the female Anopheles mosquito vector and vertebrate host. In this review, we will focus on the molecular mechanisms of the immune evasion strategies used by the Plasmodium parasite at the blood stage which is responsible for the clinical manifestations of human malaria. We also aim to provide some insights on the potential targets for malaria interventions through the recent advancement in understanding the molecular biology of the parasite.
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