4.7 Article

Visible-light-mediated direct synthesis of phosphorotrithioates as potent anti-inflammatory agents from white phosphorus

期刊

ORGANIC CHEMISTRY FRONTIERS
卷 6, 期 2, 页码 190-194

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c8qo01087k

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资金

  1. NSFC [21772163, 21778042]
  2. Natural Science Foundation of Fujian Province of China [2018J01132]
  3. NFFTBS [J1310024]
  4. Fundamental Research Funds for the Central Universities [20720160030, 20720180051]

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The reaction of P-4 with arylthiols in the presence of Na-2-eosin Y under visible light gave phosphorotrithioites. Subsequent oxidation of phosphorotrithioites produced phosphorotrithioates. The phosphorotrithioate 3f presents good inflammation reducing characteristics.

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