期刊
FIBERS
卷 7, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/fib7010006
关键词
polypropylene; hernia meshes; surface functionalization; polydopamine
资金
- 111 project Biomedical Textile Material Science and Technology [B07024]
- National Key Research and Development Program of China [2016YFB0303300-03]
- Fundamental Research Funds for the Central Universities [17D110111, 2232018G-01]
An ideal hernia mesh is one that absorbs drugs and withstands muscle forces after mesh implantation. Polypropylene (PP) mesh devices have been accepted as a standard material to repair abdominal hernia, but the hydrophobicity of PP fibers makes them unsuitable to carry drugs during the pre-implantation of PP meshes. In this study, for the first time, one-step functionalization of PP mesh surfaces was performed to incorporate bio-inspired polydopamine (PDA) onto PP surfaces. All PP mesh samples were dipped in the same concentration of dopamine solution. The surface functionalization of PP meshes was performed for 24 h at 37 degrees C and 80 rpm. It was proved by scanning electron microscopic (SEM) images and Fourier Transform Infrared Spectroscopy (FTIR) results that a thin layer of PDA was connected with PP surfaces. Moreover, water contact angle results proved that surface functionalized PP meshes were highly hydrophilic (73.1 degrees) in comparison to untreated PP mesh surfaces (138.5 degrees). Thus, hydrophilic PP meshes with bio-inspired poly-dopamine functionalization could be a good choice for hernia mesh implantation.
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