A Facile Iodine-Promoted Enals-Based cis-Selective Construction of Aziridine-2-aldehyde in Water

Direct I-2-catalyzed novel aziridination of [E]-cinnamaldehyde using Chloramine-T as nitrogen transfer agent and (BTEAC) as phase transfer catalyst is reported. Operational simplicity, excellent yield of pure products (84-93%), excellent diastereoselectivity (95-99%) in favour of cis isomer, ambient reaction conditions and using water as solvent are the salient features of envisaged methodology for direct conversion of enals into tosylaziridines.