4.6 Article

Synthesis of 4-(1H-isochromen-1-yl)isoquinolines through the silver-catalysed homodimerization of ortho-alkynylarylaldehydes and subsequent condensation of the 1,5-dicarbonyl motif with NH3

期刊

RSC ADVANCES
卷 9, 期 5, 页码 2703-2707

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ra09269a

关键词

-

资金

  1. NSFC [21402106]
  2. Shandong Natural Science Foundation [ZR2018JL013, ZR2014BQ024]
  3. Research Start-up Foundation of Qufu Normal University [bsqd20130115]

向作者/读者索取更多资源

4-(1H-Isochromen-1-yl) isoquinoline derivatives were synthesized in high yields via the AgBF4-catalyzed self-reaction of ortho-alkynylarylaldehydes to give isochromene intermediates, followed by the dehydration of the 1,5-dicarbonyl motif with NH3. Compared with electron-rich aromatic substituents, this strategy can provide the desired isochromene products with an electron-deficient isoquinoline unit. The reactions feature simple experimental operations, mild reaction conditions and high product yields.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据