期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 11, 页码 1651-1654出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc09359h
关键词
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资金
- National Natural Science Foundations of China [21864005, 81460544, 201575031]
- Natural Science Foundations of Guangxi Province [2015GXNSFGA139003, 2017GXNSFGA198004]
- BAGUI Scholar Program
- State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources [CMEMR2015-A08]
We develop a novel peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of tumor-related proteases in living cells. This nanoprobe responds rapidly and selectively, enabling simultaneous and high-contrast imaging of multiple proteases in living cells. Furthermore, it could detect the changes of protease expression in living cells.
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