期刊
ELECTROANALYSIS
卷 27, 期 12, 页码 2820-2828出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201500180
关键词
Amperometry; benzo[c]cinnoline; L-lactate; redox mediator; multiwalled carbon nanotubes
资金
- Namik Kemal University Research Fund [NKUBAP.00.10.YL.12.04]
- Ankara University Research Fund [14L0430005]
Amperometric lactate biosensor based on a carbon paste electrode modified with benzo[c]cinnoline and multiwalled carbon nanotubes is reported. Incorporation of benzo[c] cinnoline acting as a mediator and multiwalled carbon nanotubes providing a conduction pathway to accelerate electron transfer due to their excellent conductivity into carbon paste matrix resulted in a high performance lactate biosensor. The resulting biosensor exhibited a fast response, high selectivity, good repeatability and storage stability. Under the optimal conditions, the enzyme electrode showed the detection limit of 7.0 x 10(-8) M with a linear range of 2.0 x 10(-7) M-1.1 x 10(-4) M. The usefulness of the biosensor was demonstrated in serum samples.
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