Fabrication of a Nanostructure Based Electrochemical Sensor for Voltammetric Determination of Epinephrine, Uric Acid and Folic Acid

A carbon paste electrode (CPE) was modified by incorporation of graphene nano sheets and a ferrocene derivative. The modified electrode showed an excellent electrocatalytic effect on the oxidation of epinephrine. In phosphate buffer solution (PBS) of pH 7.0, the oxidation current increased linearly with concentration of epinephrine in the range of 0.05-550.0 mu M and a detection limit (3 sigma) 27.0 nM was obtained for epinephrine. Then the modified electrode was used to determine epinephrine in an excess of uric acid and folic acid by SWV.