期刊
ELECTROANALYSIS
卷 27, 期 8, 页码 1855-1863出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/elan.201500107
关键词
Multiwalled carbon nanotubes; Chitosan; Drug-DNA interactions; Electrochemical biosensors; Mitomycin C
资金
- TUBITAK [2210-C]
A multiwalled carbon nanotubes (CNT)-chitosan (CHIT) modified pencil graphite electrode (CNT-CHIT/PGE) was developed for the first time herein for electrochemical monitoring of the interaction of an anticancer drug, mitomycin C (MC) and DNA. The characterization of unmodified PGE, CHIT/PGE, CNT/PGE and CHIT-CNT/PGE were performed by scanning electron microscopy and cyclic voltammetry techniques. The oxidation signals of MC and guanine were measured before and after interaction at the surface of CNT-CHIT/PGEs using differential pulse voltammetry. Electrochemical impedance spectroscopy technique was also successfully utilized for monitoring of the interaction process at the surface of CNT-CHIT/PGEs in different interaction times.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据