期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 17, 期 3, 页码 461-466出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob02765j
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资金
- JSPS KAKENHI [16H06453]
- AMED [18061402]
- JSPS A3 Foresight Program [16822333]
The natural product A-94964 is a uridine-derived nucleoside antibiotic isolated from Streptomyces sp. SANK 60404. In this study, we propose a biosynthetic pathway for A-94964 using gene deletion experiments coupled with in silico analysis of the biosynthetic gene cluster. This study provides insights into the unique biosynthetic pathway for A-94964.
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