期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 8, 页码 1164-1167出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc09956a
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资金
- NNSFC [21432044, 21772099, 91527301]
- Programs of Higher-level Talents of Inner Mongolia Agricultural University [NDGCC2016-21]
- Inner Mongolia Autonomous Region Natural Science Fund Project [2017BS0206]
A pH-responsive and targeted polysaccharide conjugate was fabricated from the boronate linkage of N-(2-aminoethyl)-gluconamide-grafted hyaluronic acid with anticancer drug bortezomib, which could exhibit targeted drug release behaviors at acidic pH and possess lower cytotoxicity and a higher inhibition effect toward cancer cells.
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