期刊
MICROBIAL PATHOGENESIS
卷 107, 期 -, 页码 17-28出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.micpath.2017.03.010
关键词
MRSA; Typing; SCCmec; Molecular methods
资金
- National Key Research and Development Program of China [2016YFD04012021]
- Pearl River S&T Nova Program of Guangzhou
- National Outstanding Doctoral Dissertation Funding [201459]
- Guangdong Outstanding Doctoral Dissertation Funding [K3140030]
- Open Project Program of Key Laboratory for Green Chemical Process of Ministry of Education in Wuhan Institute of Technology [GCP201506]
Methicillin-resistant Staphylococcus aureus (MRSA) is a common pathogen in hospitals and the community. As the rapid spread and wide distribution of antimicrobial resistance (such as MRSA), treatment for infectious diseases caused by microorganisms has become a vital threat. Thus, early identification and genotyping are essential for further therapeutic treatment and the control of rapid expansion of MRSA. In combination with applications and data feedbacks, this review focused on the currently available molecular-based assays on their utility and performance for rapid typing of MRSA, especially on effective molecular-based methods. Besides, a common mobile element SCCmec and prevalence of HA-MRSA, LA-MRSA and CA-MRSA were introduced in this review in order to provide a more complete profile of MRSA. (C) 2017 Elsevier Ltd. All rights reserved.
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