4.5 Article

New results on the safety of laparoscopic sleeve gastrectomy bariatric procedure for type 2 diabetes patients

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WORLD JOURNAL OF DIABETES
卷 10, 期 2, 页码 78-86

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BAISHIDENG PUBLISHING GROUP INC
DOI: 10.4239/wjd.v10.i2.78

关键词

Bariatric surgery; Laparoscopic sleeve gastrectomy; Type 2 diabetes; Complications; Morbidity; Hemoglobin A1c; Fasting plasma glucose; Clavien-Dindo classification

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BACKGROUND It has been established that bariatric surgery, including laparoscopic sleeve gastrectomy (LSG), has a positive impact on type 2 diabetes mellitus (T2DM). However, less frequently T2DM is reported as a risk factor for complications with this type of surgery. AIM To evaluate the safety of LSG in T2DM. METHODS A retrospective cohort study was conducted over patients admitted for LSG from January 2008 to May 2015. Data was collected through digitized records. Any deviation from normal postoperative care within the first 60 d was defined as an early complication, and further categorized into mild or severe. RESULTS Nine hundred eighty-four patients underwent LSG, among these 143 (14.5%) were diagnosed with T2DM. There were 19 complications in the T2DM group (13.3%) compared to 59 cases in the non-T2DM (7.0%). Out of 19 complications in the T2DM group, 12 were mild (8.4%) and 7 were severe (4.9%). Compared to the non-T2DM group, patients had a higher risk for mild complications (Odds-ratio 2.316, CI: 1.163-4.611, P = 0.017), but not for severe ones (P = 0.615). An increase of 1% in hemoglobin A1c levels was associated with a 40.7% increased risk for severe complications (P = 0.013, CI: 1.074-1.843) but not for mild ones. CONCLUSION Our data suggest that LSG is relatively safe for patients with T2DM. Whether pre-operative control of hemoglobin A1c level will lower the complications rate has to be prospectively studied.

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