A new synthesis of 2-(aminoalkyl)-1,2,4-triazolo[1,5-a]pyrimidines

Nickel(H) acetylacetonate-promoted cycloaddition between Boc-protected amino acid hydrazides and benzoylcyanamide followed by deprotection gives 2-amino-5-aminoalkyl-1,2,4-triazoles, whose reaction with 1,3-dielectrophiles affords the title compounds.