期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 17, 期 7, 页码 1787-1790出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ob02600a
关键词
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资金
- Indiana University
- NIH [R01GM121573]
- IU Vice Provost for Research through the Research Equipment Fund
Herein we describe the direct enantioselective Lewis base/Pd catalysed alpha-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in a manner which points towards potential applications in target directed synthesis.
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