期刊
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
卷 49, 期 1, 页码 40-46出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1249/MSS.0000000000001063
关键词
RESISTANCE TRAINING; EPIDEMIOLOGY; WOMEN; LONGITUDINAL STUDY
资金
- National Institutes of Health [CA154647, CA047988, HL043851, HL080467, HL099355, HL007575]
- Intramural Research Program of the National Institutes of Health, National Institute on Aging
- NATIONAL CANCER INSTITUTE [UM1CA182913, R01CA154647, R01CA047988] Funding Source: NIH RePORTER
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [RC1HL099355, T32HL007575, R01HL043851, R01HL080467] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [ZIAAG006020] Funding Source: NIH RePORTER
Purpose: This study aimed to examine the association of strength training with incident type 2 diabetes and cardiovascular disease risk. Methods: We followed 35,754 healthy women (mean age = 62.6 yr, range = 47.0-97.8) from the Women's Health Study, who responded to a health questionnaire that included physical activity questions in 2000, assessing health outcomes through annual health questionnaire through 2014 (mean +/- SD follow-up = 10.7 +/- 3.7 yr). Incident type 2 diabetes (N cases = 2120) and cardiovascular disease (N cases = 1742) were confirmed on medical record review. Cases of cardiovascular disease were defined as confirmed cases of myocardial infarction, stroke, coronary artery bypass graft, angioplasty, or cardiovascular disease death. Results: Compared with women who reported no strength training, women engaging in any strength training experienced a reduced rate of type 2 diabetes of 30% (hazard ratio = 0.70, 95% confidence interval = 0.61-0.80) when controlling for time spent in other activities and other confounders. A risk reduction of 17% was observed for cardiovascular disease among women engaging in strength training (hazard ratio = 0.83, 95% confidence interval = 0.72, 0.96). Participation in both strength training and aerobic activity was associated with additional risk reductions for both type 2 diabetes and cardiovascular disease compared with participation in aerobic activity only. Conclusions: These data support the inclusion of muscle-strengthening exercises in physical activity regimens for reduced risk of type 2 diabetes and cardiovascular disease, independent of aerobic exercise. Further research is needed to determine the optimum dose and intensity of muscle-strengthening exercises.
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