期刊
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
卷 21, 期 6, 页码 3339-3346出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cp06643d
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Electroporation is a matter of intensive ongoing research interest, and a much-neglected topic in trans-membrane proteins, particularly in view of such promising potential applications in medicine and biotechnology. In particular, selected such novel and exciting applications are predicated on controlling ionic conductivity through electro-pores. Here, we scrutinise the mechanisms of ions' electric conductivity, by means of structural rearrangements, through quasi-stable electro-pores through human-AQP4 as a well-representative prototype of trans-membrane ionic conduction, achieving exquisite control over ionic permeability manipulated by the application of intense static electric fields.
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