期刊
ACS APPLIED BIO MATERIALS
卷 2, 期 3, 页码 1310-1321出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsabm.9b00012
关键词
povidone-iodine; polystyrene resin; antibacterial; biocompatibility; water bacterial decontamination
资金
- National Natural Science Foundation of China [51663019]
- State Key Laboratory of Medicinal Chemical Biology [2018051]
- Province-University Cooperation Project of Jilin Province [SXGJQY2017-4]
Bacterial contamination in water purification systems is generating significant concern as a global health issue. In this paper, we describe fabricating antibacterial povidone-iodine-conjugated cross-linked polystyrene resins (i.e., P(St-DVB-NVP)-I-2) and investigating them as antimicrobial agents for water decontamination. Comprehensive antibacterial tests showed that the addition of povidone-iodine to polystyrene resins resulted in strong antibacterial activity against pathogenic bacteria. In addition, the as-synthesized P(St-DVB-NVP)-I-2 was confirmed to have hydrophobicity and favorable biocompatibility. We then examined the possibility of using P(St-DVB-NVP)-I-2 as an antibacterial filter for water treatment and found that it could efficiently remove bacteria from water. An analog experiment demonstrated that the capability of P(St-DVB-NVP)-I-2 for water bacterial decontamination was not influenced by the presence of mineral ions in the water. Most significantly, we confirmed the potential reusability of P(St-DVB-NVP)-I-2 through a recycling test. This method of creating an antibacterial resin by building a conjugation of cross-linked polystyrene with povidone-iodine is safe, cost-effective, and environmentally friendly, and the resin shows promise for use in water purification filters.
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