期刊
PULMONARY CIRCULATION
卷 9, 期 1, 页码 -出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/2045894019834890
关键词
sudden death; prognosis; survival; atrial fibrillation; supraventricular atrial arrhythmia; atrial flutter; right heart failure
资金
- CIHR Foundation [NIH-RO1-HL071115, 1RC1HL099462]
- Tier 1 Canada Research Chair in Mitochondrial Dynamics
- William J Henderson Foundation
- CIHR Vascular Network
- Canadian Vascular Network
- Queen's Cardiopulmonary Unit (QCPU)
- Reagan Corporation
- Cushman Family
Arrhythmias are increasingly recognized as serious, end-stage complications of pre-capillary pulmonary hypertension, including pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). Although arrhythmias contribute to symptoms, morbidity, in-hospital mortality, and possibly sudden death in PAH/CTEPH, there remains a paucity of epidemiologic, pathophysiologic, and outcome data to guide management of these patients. This review summarizes the most current evidence on the topic: from the molecular mechanisms driving arrhythmia in the hypertrophied or failing right heart, to the clinical aspects of epidemiology, diagnosis, and management.
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