期刊
HEAD & NECK PATHOLOGY
卷 13, 期 1, 页码 80-90出版社
SPRINGER
DOI: 10.1007/s12105-019-01003-7
关键词
Human papillomavirus; Squamous papilloma; Oral warts; Multifocal epithelial hyperplasia; Squamous cell carcinoma; HPV transmission
类别
Human papillomaviruses (HPVs) are causative of a group of clinically papillary lesions. The HPV-related lesions of the oral cavity include squamous papilloma, condyloma acuminatum, verruca vulgaris, and multifocal epithelial hyperplasia. Benign entities, such as verruciform xanthoma or giant cell fibroma, as well as malignancies, such as papillary squamous cell carcinoma and verrucous carcinoma, may be considered in the clinical and/or histologic differential diagnoses of these lesions. Mechanisms of infection, epidemiology, clinical presentations, histologic features, and differential diagnoses of the HPV-related oral pathologies are discussed. Current concepts of viral transmission, especially as pertaining to lesions in pediatric patients, and the impacts of HPV vaccination are reviewed.
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