Characterization of human cancellous and subchondral bone with respect to electro physical properties and bone mineral density by means of impedance spectroscopy

Computational simulation of electrical bone stimulation of the electrical and dielectric parameters of osteoarthritic bone tissue is useful for an exact patient-individual adaptation of the bone models. Therefore, we investigated electrical and dielectric parameters at a frequency of 20 Hz of cancellous and subchondral human femoral head bone samples. Furthermore, the mechanical properties and the bone mineral density (BMD) were determined. Finally, these data were compared with the electrical and dielectric parameters. The bone samples were taken from patients with hip osteoarthritis. Electrical conductivity and dielectric permittivity of cancellous bone amounted to 0.043 S/m and 8.1.10(6). BMD of the bone samples determined by dual-x-ray-absorptiometry (DXA) and ashing resulted in 193 +/- 70 mg/cm(2) and 286 +/- 59 mg/cm(3), respectively. Structural modulus (E-s) and ultimate compression strength ((sigma)max) were measured with 227 +/- 94 N/mm(2) and 6.5 +/- 3.4 N/mm(2). No linear correlation of the electrical and dielectric parameters compared with BMD and mechanical properties of cancellous bone samples was found. Electrical conductivity and dielectric permittivity of subchondral bone resulted in 0.029 S/m and 8.97 x 10(6). (C) 2017 IPEM. Published by Elsevier Ltd. All rights reserved.