期刊
MATURITAS
卷 95, 期 -, 页码 31-35出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.maturitas.2016.10.008
关键词
Ageing; Frailty; Non-communicable disease; Chronic disease; Multimorbidity; Comorbidity
资金
- Instituto de Salud Carlos III, Fondo de Investigacion Sanitaria, Ministerio de Sanidad y Consumo, Madrid, Spain [PI12/02775]
- European Regional Development Fund (ERDF)
The extension of life expectancy is a global phenomenon. The growth in the ageing population has created a new health scenario in which there is a higher prevalence of frailty and multimorbidity. The attention received by both conditions derives from their strong association with disability, hospitalization, and death. The aim of the present paper is to conceptualize and differentiate these terms and to discuss their interrelations. We conclude that, yet related, they represent two different clinical conditions. Frailty identifies the increased vulnerability to stressors due to a dynamic, non-linear, and multidimensional depletion of physiological reserve and redundancy, whereas multimorbidity refers to the coexistence of two or more clinically manifest chronic diseases. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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