期刊
MATURITAS
卷 99, 期 -, 页码 10-15出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.maturitas.2017.01.012
关键词
Genitourinary syndrome of menopause; Urinary incontinence; Pelvic organ prolapse; Vaginal relaxation syndrome; Vaginal laser therapy
资金
- Bayer
- MSD
- Gedeon Ritcher
- Novo Nordisk
- Pfizer
- Shionogi
- TEVA
- Servier
- Daiichi Sankyo
- Amgen
- Serelys
- Exeltis
- Bayer Healthcare
- Procareh Health
Laser therapy has a therapeutic role in various medical conditions and most recently has gained interest as a non-hormonal treatment for genitourinary syndrome of menopause (GSM) and as a non-invasive option for stress urinary incontinence (SUI). Several therapies are available to alleviate GSM symptoms, including hormonal and non-hormonal products. Both microablative fractional CO2 laser and the non ablative vaginal Er:YAG laser (VEL) induce morphological changes in the vaginal tissues, and data from non-randomized clinical trials suggest that laser therapy can alleviate vaginal dryness and dyspareunia. VEL has been reported to improve SUI as well as vaginal prolapse. Although large randomized trials have not been reported, the evidence suggests that VEL can be offered as a safe and efficacious alternative to hormone replacement therapy (HRT) for GSM, as well as a first-line treatment for mild to moderate SUI, before surgical procedures are resorted to. Randomized studies are needed to compare laser treatments with other therapies, as well as to assess the duration of the therapeutic effects and the safety of repeated applications. Research is presently evaluating both an automated robotic probe for VEL treatments and an intraurethral probe for the treatment of severe and type III SUI. (C) 2017 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据