期刊
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
卷 79, 期 -, 页码 720-727出版社
ELSEVIER
DOI: 10.1016/j.msec.2017.05.122
关键词
Biosynthesis; Silver nanoparticles; Viburnum opulus L; Anti-inflammatory activity
资金
- Ministry of National Education and Scientific Research, Romania [147/2012 PN-II-PT-PCCA-2011-3-1-0914]
A green, rapid and cost effective method for the bio-synthesis of silver nanoparticles (AgNPs), using polyphenols present in European cranberry bush fruit extracts was developed. The obtained AgNPs were characterized by ultra-violet visible spectroscopy (UV-VIS), Fourier transform - infrared spectroscopy (FT-IR), transmission electron microscopy (TEM) and X-ray diffraction patterns (XRD). The average size of the spherical AgNPs was found to be 25 nm. The anti-inflammatory effect of the biomaterials was investigated, both in vitro (on HaCaT cell line, exposed to UVB radiation) and in vivo (on acute inflammation model in Wistar rats). Our results support the conclusion that the photosynthesized silver nanoparticles present a potent anti-inflammatory activity and could be successfully used as therapeutic tools for treatment of inflammation. (C) 2017 Elsevier B.V. All rights reserved.
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