Facile biosynthesis of antimicrobial zinc oxide (ZnO) nanoflakes using leaf extract of Couroupita guianensis Aubl.

Here, we report a facile green chemistry route to synthesize zinc oxide (ZnO) nanoflakes using the leaf extract of C guianensis Aubl. (CGLE) as a potential bioreductant. Heterocyclic active constituents present in CGLE predominantly influences the reduction and forms a complexation with ZnO nanomaterials. XRD analysis confirms the growth of hexagonal ZnO with the corresponding planes at 31.8 degrees (100), 34.5 degrees (002), 36.3 degrees (101), 47.6 degrees (102), 56.6 degrees (110), 62.9 degrees (103), 66.4 degrees (002), 67.9 degrees (112), 69.0 degrees (201), and 76.9 degrees (202). Further, it was also demonstrated that the fabricated ZnO was highly stable possessing negative zeta value (-20.7 mV) and UV-Visible spectroscopy has shown the absorbance maxima at 367 nm. Interestingly, synthesized ZnO nanomaterials exhibits an excellent bactericidal effect against human pathogens and displays very less hemoglobin release, which clearly depicts its suitability to use in diverse nanomedicinal applications. (C) 2016 Elsevier B.V. All rights reserved.