期刊
MATERIALS LETTERS
卷 196, 期 -, 页码 213-216出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.matlet.2017.03.065
关键词
Biomaterials; Thin films; Polymers; Biomimetic; Surfaces
资金
- FWO, Belgium
- BOF UGent
- ERA-Net Rus Plus project Intelbiocomp
- European Union [613931]
- European Research Council under the European Union [279022]
Coating biomedical implant surfaces with biopolymers is an easy and inexpensive way to impart functionalities. Numerous biocompatible biopolymers, including cationic crustacean-derived chitosans, have been used. Here, substrates of Titanium (Ti), commonly used for bone contact applications, were coated with chitosan and one of three polyphenol-rich plant extracts (PPrPE) and characterized physicochemically. Hela cell adhesion and growth of methicillin-resistant Staphylococcus aureus (MRSA) were studied. Chitosan and PPrPE on surfaces were detected by FTIR and XPS. Chitosan coatings, both with and without PPrPE functionalization, did not inhibit MRSA growth and promoted Hela cell adhesion. The effect of PPrPE functionalization remained unclear. (C) 2017 Elsevier B.V. All rights reserved.
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