Facile synthesis of mesoporous bioactive glass nanospheres with large mesopore via biphase delamination method

This work focused on fabricating mesoporous bioactive glass nanospheres with large pore (LMBGs) by means of a biphase delamination approach and the self-assembly of the reactants took place at the oil-water interface. The morphology and mesostructure of LMBGs were investigated and the results demonstrated that the well-dispersed LMBGs with a radial mesoporous structure and large pore size could be easily tuned by adjusting the reaction temperature using hexadecyl trimethyl ammonium bromide (CTAB) as a template agent and triethanolamine (TEA) as a hydrolysis catalyst. The special structure and outstanding property of LMBGs probably endowed it with a bright prospect in the application of drug delivery systems. (C) 2017 Published by Elsevier B.V.