期刊
BIOMOLECULES
卷 9, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/biom9030094
关键词
Resveratrol; bone-regeneration; craniofacial tissue; alveolar bone loss; bone defect; resveratrol scaffold
资金
- Ministero dell'Istruzione dell'Universita e della Ricerca (MIUR) [2017-2018-prot, DOT1320875]
The natural polyphenol Resveratrol (RSV) claims numerous positive effects on health due to the well documented biological effects demonstrating its potential as a disease-preventing agent and as adjuvant for treatment of a wide variety of chronic diseases. Since several studies, both in vitro and in vivo, have highlighted the protective bone aptitude of RSV both as promoter of osteoblasts' proliferation and antagonist of osteoclasts' differentiation, they could be interesting in view of applications in the field of dentistry and maxillofacial surgery. This review has brought together experimental findings on the use of RSV in the regeneration of bone tissue comprising also its application associated with scaffolds and non-transfusional hemocomponents.
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