期刊
JOURNAL OF ORTHOPAEDICS AND TRAUMATOLOGY
卷 20, 期 1, 页码 -出版社
SPRINGER
DOI: 10.1186/s10195-019-0528-0
关键词
Diamond concept; Bone healing; Long bone; Non-union; Mesenchymal stem cells
类别
Long bone non-union continues to be a significant worldwide problem. Since its inception over a decade ago, the 'diamond concept', a conceptual framework of what is essential for a successful bone healing response, has gained great acceptance for assessing and planning the management of fracture non-unions. Herein, we discuss the epidemiology of non-unions, the basic science of bone healing in the context of the diamond concept, the currently available results and areas for future research.
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