Gold(I) catalysed regio- and stereoselective intermolecular hydroamination of internal alkynes: towards functionalised azoles

Gold(I) catalysed regio- and stereoselective intermolecular hydroamination of internal alkynes was developed for the effective synthesis of a series of (Z)-functionalised vinylazoles under solvent free conditions. The catalytic hydrogenation of the resulting enamines leads to substituted saturated azoles in good yields.