期刊
BIOMATERIALS SCIENCE
卷 7, 期 4, 页码 1281-1285出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8bm01466c
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资金
- Spanish Government (Ramon y Cajal grant)
- Spanish Government [MAT2015-67183-R, MAT2017-83905-R]
- Government of Catalonia [2017 SGR-116533]
- Government of Catalonia (predoctoral FI fellowship)
- Government of Catalonia (ICREA academia fellowship)
- EU's Seventh Framework Programme (FP7-PEOPLE-2012-CIG) [321985]
- Government of Korea [2009-0093829, 2015032163]
- National Research Foundation, Republic of Korea (GRDC Program) [NRF-2018K1A4A3A01064257]
In this communication we report that anchoring v3 or 51 integrin-selective RGD peptidomimetics to titanium efficiently tunes mesenchymal stem cell response in vitro and bone growth in rat calvarial defects. Our results demonstrate that this molecular chemistry-derived approach could be successful to engineer instructive coatings for orthopedic applications.
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