4.5 Article

A multi-interpenetrating network (IPN) hydrogel with gelatin and silk fibroin

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BIOMATERIALS SCIENCE
卷 7, 期 4, 页码 1276-1280

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c8bm01532e

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  1. NIH COBRE Center of Integrated Biomedical and Bioengineering Research (CIBBR) through an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences [P20 GM113131]

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A mechanically strong composite hydrogel was produced based on an interpenetrating network (IPN) between gelatin and silk fibroin. When two layers of the IPN were created, the resulting hydrogel exhibited much improved mechanical properties. This hydrogel is biodegradable and non-cytotoxic and allows for cell adhesion and proliferation on the surface.

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