DIVERGENT SYNTHESIS OF STEROID ANALOGS FROM STEROIDAL β-FORMYLENAMIDES, CONJUGATED ENONES AND β-FORMYLVINYL HALIDES

In the past two decades, our laboratory has been actively engaged in the design and synthesis of novel heterosteroidal analogues. Three functional groups namely beta-formylenamide, conjugated enone and beta-formylvinyl halide were primarily employed in various reactions to afford a library of novel heterosteroids. The synthetic strategies have been concomitantly utilized in the relevant non-steroidal beta-formylenamides, conjugated enones and beta-formylvinyl halides.