期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 36, 页码 5243-5246出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc01832h
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Herein, we have designed a ratiometric fluorescent nanoprobe for adenosine triphosphate sensing and imaging in living cells, based on silica nanoparticles and a DNA-functionalized hybrid hydrogel. This ratiometric detecting method could validly avoid false-positive signals. Due to its controllable size, favorable biocompatibility and biostability, the nanohydrogel exhibited high cellular permeability and fast response in living cells.
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