期刊
LANGMUIR
卷 33, 期 13, 页码 3234-3240出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.langmuir.6b03986
关键词
-
资金
- National Natural Science Foundation of China [21434008, 21674054]
Smart hydrogels have received increasing attention for many applications. Here, we synthesized a class of cationic peptide amphiphiles that can self-assemble into hydrogels by ring-opening polymerization (ROP) and post modification strategy. The incorporation of cationic lysine residues suppresses the formation of fibril-like structure and further the gelation ability of the samples. Sodium alginate (SA) is used to enhance the rheology performance of the hydrogels. The hydrogels exhibit pH-dependent self-assembly and the gelation behavior that enables them to be ideal smart hydrogel systems for biomedical applications. Furthermore, the as-prepared hybrid peptide hydrogels show antibacterial activity.
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