期刊
LAB ON A CHIP
卷 17, 期 2, 页码 286-292出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6lc00911e
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资金
- Basic Science Research Program of the National Research Foundation of Korea [2014R1A1A1038270]
- Korean government (MSIP) [NRF-2016R1A5A1010148]
- National Research Foundation of Korea [2014R1A1A1038270] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Generating periodic flows with an oscillator driven only by water-head pressure has potential for the operation of microfluidic systems without any dynamic off-chip controllers. However, its operational characteristic is not well understood due to complex dynamic interactions of the microfluidic components. Here, we focus on the mechanism of a water-head-driven oscillator and analyze the functions of its flowswitching period (T) and flow rate (Q) in a wide range (0.1 s-5.9 h and 2 mu L min(-1) -2 mLmin(-1)). We show linear control of T and Q by their corresponding fluidic resistors even with the complex and nonlinear relation of the microfluidic components. This allows independent regulation of T and Q within their operational ranges but we found the two parameters mutually constrain their ranges via fluidic resistance. Also, we characterize the control of T by water-head pressure and present operational ranges of input water-head pressure decrease with increasing output water-head pressure. To show its utility, we apply the oscillator to generate droplets with low interfacial tension aqueous two-phase systems. Our study would be useful and provide the foundation for various functions of water-head-driven microfluidic circuits.
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